The embryo, predicted in 3D

We are building a 3D gene-expression predictor powered by Pillar, a spatiotemporal foundation model of development, together with Dynode, a method for spatiotemporal dynamical modeling. The visualization below is an early demo — a spatiotemporal reconstruction of mouse embryogenesis from E7.8 to E12.5, with cell types and marker-gene expression rendered cell-by-cell across ten timepoints.

Drag to orbit, scrub the timepoint, and switch view inside the frame — the 2D / 3D-point / 3D-section reconstructions, plus the new perturbation forecast: a Dynode 50-step prediction of a Foxf1 perturbation at E8.2, swept across the cardiac field and the whole embryo. The Pillar model itself will be released soon.

Visualization by the Qiu Lab. Part of the predictive virtual embryo effort.